AP Biology Flashcards: Complete 8-Unit Course Review

Review all 8 AP Biology units with original flashcards for concepts, pathways, experimental design, data interpretation, and FRQ reasoning.

About this deck

AP Biology Flashcards: Complete 8-Unit Course Review

The current AP Biology framework covers eight units, from chemistry of life through ecology. This 540-card deck turns that full course into short, original retrieval prompts, with science-practice reasoning mixed into the biology instead of parked in a separate section.

What the cards practice

The cards connect terms to functions, structures to consequences, pathway steps to inputs, outputs, locations, and regulation, and evidence to biological claims. Separate prompts cover useful reverse mappings when they are real study tasks—for example, identifying a process from its location or choosing the inference supported by a result. Short original scenarios also practice describing patterns, explaining mechanisms, predicting changes, justifying claims, setting up calculations, and evaluating evidence.

The deck does not mechanically reverse every definition or pathway. It leaves out copied exam material, scoring language, official figures, exhaustive protocols, broad essay prompts, textbook-specific trivia, and advanced-college details outside the current course boundary.

Learning order

The sequence follows Units 1–8. Within each unit it moves from prerequisites to processes, applications, experiments, data, and FRQ-style reasoning, while spacing close variants apart. Long-term spacing and interleaving are left to the review scheduler.

What still needs practice

Flashcards are useful for recall and small reasoning moves, but they cannot replace laboratory work, graph construction, extended data analysis, or timed multiple-choice and free-response practice. Use the deck beside class labs and full original practice questions.

Scope and provenance

The course boundary was reviewed on September 1, 2026 against the College Board AP Biology course page, the Fall 2025 Course and Exam Description, its current clarifications and corrections, the 2026–27 course-change table, and the current exam page. The selection, prompts, answers, examples, sequence, metadata, and cover are independently created from common biological knowledge and source checks. No exam questions, scoring guidelines, CED text, answer keys, or official figures were copied or transformed.

The Common knowledge · CC0 1.0 label applies to the original wording, organization, metadata, and generated media to the extent applicable rights exist. It does not claim ownership of biological facts, AP or College Board names, or third-party source material.

This independent, unofficial study deck is not affiliated with, endorsed by, or sponsored by College Board. AP and College Board names identify the course and exam only. Official requirements: https://apcentral.collegeboard.org/courses/ap-biology

Cards in this deck

  1. Card 1

    Question

    Why is a water molecule polar?

    Answer

    Oxygen pulls shared electrons more strongly than hydrogen, giving oxygen a partial negative charge and the hydrogens partial positive charges.

  2. Card 2

    Question

    Which elements make up most biological molecules?

    Answer

    Carbon, hydrogen, oxygen, nitrogen, phosphorus, and sulfur—often shortened to CHNOPS.

  3. Card 3

    Question

    What is the relationship between a monomer and a polymer?

    Answer

    Monomers are small building blocks; polymers are chains or networks made from repeated monomers.

  4. Card 4

    Question

    What is a monosaccharide's main role in cells?

    Answer

    It can provide quick energy and serve as a building block for larger carbohydrates.

  5. Card 5

    Question

    Why do lipids mix poorly with water?

    Answer

    Most of their bonds are nonpolar, so water cannot form favorable interactions with them.

  6. Card 6

    Question

    What three parts make up a nucleotide?

    Answer

    A five-carbon sugar, a phosphate group, and a nitrogenous base.

  7. Card 7

    Question

    What parts of an amino acid vary and stay constant?

    Answer

    The amino group, carboxyl group, hydrogen, and central carbon are shared; the side chain, or R group, varies.

  8. Card 8

    Question

    What does pH measure?

    Answer

    The negative logarithm of hydrogen-ion concentration; lower pH means more hydrogen ions.

  9. Card 9

    Question

    What is a hydrogen bond in liquid water?

    Answer

    A weak attraction between a partially positive hydrogen on one water molecule and a partially negative oxygen on another.

  10. Card 10

    Question

    How does an unsaturated fatty acid differ from a saturated one?

    Answer

    An unsaturated fatty acid has at least one carbon–carbon double bond; a saturated fatty acid has none.

  11. Card 11

    Question

    What bond links amino acids in a polypeptide?

    Answer

    A peptide bond.

  12. Card 12

    Question

    What does dehydration synthesis do?

    Answer

    It joins subunits with a covalent bond while removing the elements of water.

  13. Card 13

    Question

    How does cohesion help water move through a plant?

    Answer

    Hydrogen bonds keep water molecules linked, helping a continuous column rise through xylem.

  14. Card 14

    Question

    How do plants and animals differ in short-term glucose storage?

    Answer

    Plants store glucose mainly as starch; animals store it mainly as glycogen.

  15. Card 15

    Question

    What determines a protein's primary structure?

    Answer

    Its amino-acid sequence.

  16. Card 16

    Question

    How does a cis double bond affect a fatty-acid tail?

    Answer

    It introduces a bend that prevents neighboring tails from packing tightly.

  17. Card 17

    Question

    How does adhesion support water transport in narrow tubes?

    Answer

    Water sticks to polar surfaces, helping it resist gravity along cell walls.

  18. Card 18

    Question

    Which base pairing distinguishes RNA from DNA?

    Answer

    RNA uses uracil, so adenine pairs with uracil instead of thymine.

  19. Card 19

    Question

    What stabilizes common protein secondary structures?

    Answer

    Hydrogen bonds between atoms in the polypeptide backbone.

  20. Card 20

    Question

    Why can carbon form so many biological structures?

    Answer

    It has four valence electrons and can form four stable covalent bonds, including chains, branches, and rings.

  21. Card 21

    Question

    Why can some insects stand on water?

    Answer

    Cohesion among surface water molecules creates high surface tension.

  22. Card 22

    Question

    What does hydrolysis do to a biological polymer?

    Answer

    It adds the elements of water to break a covalent bond between subunits.

  23. Card 23

    Question

    What carbohydrate strengthens plant cell walls?

    Answer

    Cellulose.

  24. Card 24

    Question

    Why are fats useful for long-term energy storage?

    Answer

    Their many C–H bonds store substantial chemical energy, and hydrophobic storage adds little water mass.

  25. Card 25

    Question

    How does water buffer rapid temperature change?

    Answer

    Breaking and forming many hydrogen bonds absorbs or releases substantial heat, giving water a high specific heat.

  26. Card 26

    Question

    What does antiparallel mean for a DNA double helix?

    Answer

    Its two strands run in opposite directions: one 5′→3′ and the other 3′→5′.

  27. Card 27

    Question

    What mainly drives a protein's tertiary structure?

    Answer

    Interactions among side chains, including hydrophobic interactions, ionic bonds, hydrogen bonds, and disulfide bridges.

  28. Card 28

    Question

    What is a trace element?

    Answer

    An element an organism needs in very small amounts, such as iron in many electron-transfer proteins.

  29. Card 29

    Question

    Why does sweating cool an organism?

    Answer

    The fastest water molecules escape as vapor, carrying heat away from the surface.

  30. Card 30

    Question

    A cell builds a polysaccharide from sugars. Is water consumed or released?

    Answer

    Released. Forming each linkage by dehydration removes water.

  31. Card 31

    Question

    Why can branching help a storage polysaccharide release glucose quickly?

    Answer

    More branch ends give enzymes more sites to work at once.

  32. Card 32

    Question

    What makes a phospholipid amphipathic?

    Answer

    It has a polar, hydrophilic head and nonpolar, hydrophobic tails.

  33. Card 33

    Question

    Where is biological information encoded in a nucleic acid?

    Answer

    In the linear sequence of nucleotide bases.

  34. Card 34

    Question

    What is quaternary protein structure?

    Answer

    The arrangement of two or more polypeptide subunits into one functional protein.

  35. Card 35

    Question

    Why does ice float on liquid water?

    Answer

    Stable hydrogen bonds hold ice molecules in an open lattice, making ice less dense than liquid water.

  36. Card 36

    Question

    How does electronegativity affect a covalent bond?

    Answer

    A difference in attraction for electrons makes electron sharing unequal and can create a polar bond.

  37. Card 37

    Question

    A digestive reaction adds water while splitting a macromolecule. What reaction is this?

    Answer

    Hydrolysis.

  38. Card 38

    Question

    What links monosaccharides in a polysaccharide?

    Answer

    Glycosidic covalent bonds.

  39. Card 39

    Question

    Why do phospholipids form bilayers in water?

    Answer

    Hydrophilic heads face water while hydrophobic tails cluster away from it.

  40. Card 40

    Question

    To which end are nucleotides added during nucleic-acid synthesis?

    Answer

    The 3′ end of the growing strand.

  41. Card 41

    Question

    Why can one amino-acid substitution change protein function?

    Answer

    It can alter side-chain interactions, folding, stability, or an active or binding site.

  42. Card 42

    Question

    How does a buffer resist a pH change?

    Answer

    It can accept added hydrogen ions or donate them when hydrogen-ion concentration falls.

  43. Card 43

    Question

    Why is water a useful solvent for cells?

    Answer

    Its partial charges surround ions and other polar molecules, separating and dispersing them.

  44. Card 44

    Question

    Why do functional groups matter in organic molecules?

    Answer

    They give carbon skeletons predictable chemical properties, such as polarity, acidity, or reactivity.

  45. Card 45

    Question

    Why can two polymers built from similar monomers have different functions?

    Answer

    Their monomer sequence, branching, length, and three-dimensional shape can differ.

  46. Card 46

    Question

    A seedling consumes stored starch. What happens to the starch?

    Answer

    Hydrolysis breaks it into smaller sugars that can enter energy pathways.

  47. Card 47

    Question

    What are two biological roles of steroids?

    Answer

    Some act as signaling molecules, and cholesterol helps stabilize animal cell membranes.

  48. Card 48

    Question

    What bond forms the backbone of a nucleic-acid strand?

    Answer

    Covalent phosphodiester bonds link the sugar of one nucleotide to the phosphate of the next.

  49. Card 49

    Question

    What does denaturation do to a protein?

    Answer

    It disrupts the protein's three-dimensional shape and often its function without usually breaking the primary peptide chain.

  50. Card 50

    Question

    An enzyme works best near pH 7 but slows at pH 3. What is a likely explanation?

    Answer

    Extra hydrogen ions changed charges and interactions that maintain the enzyme's active shape.

  51. Card 51

    Question

    What structure encloses every cell?

    Answer

    A plasma membrane.

  52. Card 52

    Question

    What is the nucleus's main function?

    Answer

    It houses most eukaryotic DNA and is a major site of DNA replication and transcription.

  53. Card 53

    Question

    Why does surface-area-to-volume ratio fall as a cell grows?

    Answer

    Volume increases with the cube of length, while surface area increases with the square.

  54. Card 54

    Question

    What does the fluid mosaic model describe?

    Answer

    A dynamic phospholipid bilayer containing mobile proteins, sterols, and carbohydrates.

  55. Card 55

    Question

    What drives simple diffusion?

    Answer

    Random molecular motion produces net movement from higher to lower concentration.

  56. Card 56

    Question

    How does active transport differ from facilitated diffusion?

    Answer

    Active transport moves a substance against its gradient using energy; facilitated diffusion moves it down a gradient.

  57. Card 57

    Question

    Why does compartmentalization increase cellular efficiency?

    Answer

    It concentrates enzymes and substrates and maintains distinct conditions for different reactions.

  58. Card 58

    Question

    When should a light microscope be preferred over an electron microscope?

    Answer

    When observing living cells or dynamic processes at lower resolution.

  59. Card 59

    Question

    What does the nucleolus produce?

    Answer

    Ribosomal RNA and early ribosome subunits.

  60. Card 60

    Question

    Does passive transport require direct cellular energy?

    Answer

    No. It moves substances down an electrochemical or concentration gradient.

  61. Card 61

    Question

    What feature separates prokaryotic from eukaryotic cells?

    Answer

    Eukaryotic cells have a membrane-bound nucleus and other membrane-bound organelles; prokaryotic cells do not.

  62. Card 62

    Question

    Which membrane region blocks most ions and polar molecules?

    Answer

    The hydrophobic interior formed by phospholipid tails.

  63. Card 63

    Question

    What happens on rough endoplasmic reticulum?

    Answer

    Bound ribosomes make proteins for secretion, membranes, or the endomembrane system.

  64. Card 64

    Question

    How does facilitated diffusion differ from simple diffusion?

    Answer

    It uses a channel or carrier protein but still moves a substance down its gradient.

  65. Card 65

    Question

    Where is prokaryotic DNA usually located?

    Answer

    In a nucleoid region rather than inside a membrane-bound nucleus.

  66. Card 66

    Question

    How does cholesterol affect an animal membrane?

    Answer

    It buffers fluidity, limiting excess movement when warm and preventing tight packing when cool.

  67. Card 67

    Question

    What does smooth endoplasmic reticulum do?

    Answer

    It synthesizes lipids, detoxifies some compounds, and stores calcium in specialized cells.

  68. Card 68

    Question

    What determines a channel protein's selectivity?

    Answer

    Its pore size, shape, charge, and gating behavior.

  69. Card 69

    Question

    What does the sodium–potassium pump accomplish?

    Answer

    Using ATP, it exports three sodium ions and imports two potassium ions per cycle.

  70. Card 70

    Question

    What do ribosomes do in both prokaryotic and eukaryotic cells?

    Answer

    They translate mRNA into polypeptides.

  71. Card 71

    Question

    What is the Golgi apparatus's role?

    Answer

    It modifies, sorts, and packages proteins and lipids arriving from the endoplasmic reticulum.

  72. Card 72

    Question

    What is osmosis?

    Answer

    Net movement of water across a selectively permeable membrane toward lower free-water concentration.

  73. Card 73

    Question

    Why does a high surface-area-to-volume ratio help a cell?

    Answer

    It provides more membrane area per unit of cytoplasm for exchange with the environment.

  74. Card 74

    Question

    How do unsaturated phospholipid tails affect membrane fluidity?

    Answer

    Their bends reduce tight packing, usually increasing fluidity.

  75. Card 75

    Question

    Trace a secreted protein after translation begins.

    Answer

    Rough ER → transport vesicle → Golgi → secretory vesicle → plasma membrane.

  76. Card 76

    Question

    What happens to an animal cell in a hypotonic solution?

    Answer

    Water enters; the cell swells and may lyse.

  77. Card 77

    Question

    What is cotransport?

    Answer

    The downhill movement of one substance powers the uphill transport of another through the same protein.

  78. Card 78

    Question

    What is the main role of a cell wall?

    Answer

    It provides structural support and helps prevent excessive expansion.

  79. Card 79

    Question

    What do lysosomes do?

    Answer

    Their hydrolytic enzymes digest macromolecules and recycle damaged cell parts in an acidic compartment.

  80. Card 80

    Question

    What happens to an animal cell in a hypertonic solution?

    Answer

    Water leaves; the cell shrinks.

  81. Card 81

    Question

    How do intestinal microvilli improve absorption?

    Answer

    They increase membrane surface area without greatly increasing cell volume.

  82. Card 82

    Question

    What can an integral membrane protein do?

    Answer

    It can transport substances, receive signals, catalyze reactions, or anchor cell structures.

  83. Card 83

    Question

    What is a central vacuole's major role in a plant cell?

    Answer

    It stores solutes and water and helps maintain turgor pressure.

  84. Card 84

    Question

    What happens to a plant cell in a hypotonic solution?

    Answer

    Water enters and turgor pressure rises; the cell wall helps prevent bursting.

  85. Card 85

    Question

    How can a proton gradient power sucrose uptake in a plant cell?

    Answer

    Protons flow down their gradient through a symporter that carries sucrose uphill.

  86. Card 86

    Question

    What evidence supports the endosymbiotic origin of mitochondria?

    Answer

    They have double membranes, circular DNA, bacterial-like ribosomes, and divide independently by a similar process.

  87. Card 87

    Question

    Which overall energy-conversion pathway mainly occurs in mitochondria?

    Answer

    Most stages of aerobic cellular respiration and ATP production.

  88. Card 88

    Question

    What happens to a plant cell in a hypertonic solution?

    Answer

    Water leaves, turgor falls, and the membrane may pull from the wall during plasmolysis.

  89. Card 89

    Question

    Why can't a standard light microscope resolve a ribosome clearly?

    Answer

    A ribosome is smaller than the microscope's diffraction-limited resolution.

  90. Card 90

    Question

    How do bacterial and plant cell walls differ?

    Answer

    Bacterial walls usually contain peptidoglycan; plant walls contain cellulose.

  91. Card 91

    Question

    Which overall energy-conversion pathway occurs in chloroplasts?

    Answer

    Photosynthesis: converting light energy into chemical energy and fixing carbon.

  92. Card 92

    Question

    A cubical cell doubles each side length. How do surface area and volume change?

    Answer

    Surface area increases 4-fold; volume increases 8-fold.

  93. Card 93

    Question

    What is the role of membrane carbohydrates?

    Answer

    They help cells recognize and interact with one another.

  94. Card 94

    Question

    What is water potential?

    Answer

    A measure predicting water movement; water moves from higher to lower water potential.

  95. Card 95

    Question

    How do microtubules support a cell?

    Answer

    They resist compression, form tracks for motors, and build structures such as spindles, cilia, and flagella.

  96. Card 96

    Question

    What is endocytosis?

    Answer

    The plasma membrane folds inward to bring material into the cell in a vesicle.

  97. Card 97

    Question

    What evidence supports the endosymbiotic origin of chloroplasts?

    Answer

    They share bacterial-like DNA, ribosomes, division, and a double membrane consistent with engulfment.

  98. Card 98

    Question

    In a membrane-permeability test, what is the independent variable?

    Answer

    The factor deliberately changed, such as temperature or solute identity.

  99. Card 99

    Question

    How do microfilaments support cell movement?

    Answer

    Actin filaments interact with motor proteins to change cell shape, contract, and move materials.

  100. Card 100

    Question

    What does the cytosol contain?

    Answer

    Water, ions, small molecules, and proteins where many metabolic reactions occur.

  101. Card 101

    Question

    Why can diffusion limit cell size?

    Answer

    As dimensions grow, molecules must travel farther, while exchange area does not keep pace with metabolic volume.

  102. Card 102

    Question

    What does selective permeability mean?

    Answer

    The membrane allows some substances to cross more readily than others.

  103. Card 103

    Question

    What is an intermediate filament's general role?

    Answer

    It provides durable mechanical strength and helps anchor structures.

  104. Card 104

    Question

    How does adding a nonpenetrating solute affect water potential?

    Answer

    It makes solute potential, and usually total water potential, more negative.

  105. Card 105

    Question

    What is exocytosis?

    Answer

    A vesicle fuses with the plasma membrane and releases contents outside the cell.

  106. Card 106

    Question

    Why can lysosomal enzymes digest safely inside a cell?

    Answer

    A membrane isolates the acidic enzymes from most cytosolic components.

  107. Card 107

    Question

    Why include an untreated membrane sample in an experiment?

    Answer

    It provides a control baseline for judging the treatment's effect.

  108. Card 108

    Question

    Why doesn't cell size alone identify whether a cell is prokaryotic?

    Answer

    Sizes overlap; the presence or absence of internal membrane-bound structures is stronger evidence.

  109. Card 109

    Question

    Why are organelle interactions important?

    Answer

    Cell functions often require products to move through several specialized compartments rather than one organelle working alone.

  110. Card 110

    Question

    What graph would show a size constraint clearly?

    Answer

    Plot cell size on the x-axis and surface-area-to-volume ratio on the y-axis; the ratio should decline as size rises.

  111. Card 111

    Question

    Which molecules cross a phospholipid bilayer most easily without proteins?

    Answer

    Small nonpolar molecules, such as oxygen and carbon dioxide.

  112. Card 112

    Question

    Two solutions have equal water potential. What is the net water movement?

    Answer

    None, although water molecules still move both ways.

  113. Card 113

    Question

    Why is ATP loss likely to disrupt ion balance?

    Answer

    ATP-powered pumps stop maintaining gradients, so passive leaks move ions toward equilibrium.

  114. Card 114

    Question

    How does folding an internal membrane help an organelle?

    Answer

    It increases surface area for membrane-bound reactions without a matching increase in volume.

  115. Card 115

    Question

    A dye leaves heated cells faster than unheated cells. What conclusion is supported?

    Answer

    Heating increased membrane permeability under the tested conditions; the data alone do not identify the exact molecular damage.

  116. Card 116

    Question

    What does an enzyme change in a reaction?

    Answer

    It lowers activation energy, increasing reaction rate without changing the reaction's overall free-energy change.

  117. Card 117

    Question

    What makes a reaction exergonic?

    Answer

    It releases free energy and has a negative change in free energy under the stated conditions.

  118. Card 118

    Question

    What are the overall inputs and outputs of photosynthesis?

    Answer

    Carbon dioxide and water use light energy to produce carbohydrate and oxygen.

  119. Card 119

    Question

    What are the overall reactants and products of aerobic cellular respiration?

    Answer

    Organic fuel and oxygen are converted mainly to carbon dioxide, water, and ATP, with heat released.

  120. Card 120

    Question

    How should reaction rate be calculated from product data?

    Answer

    Divide the change in product amount by the elapsed time.

  121. Card 121

    Question

    What makes an enzyme substrate-specific?

    Answer

    The active site's shape and chemical properties favor particular substrates.

  122. Card 122

    Question

    Where do the light reactions occur?

    Answer

    In the thylakoid membranes of chloroplasts.

  123. Card 123

    Question

    Where does glycolysis occur?

    Answer

    In the cytosol.

  124. Card 124

    Question

    What makes a reaction endergonic?

    Answer

    It requires a net input of free energy and has a positive change in free energy.

  125. Card 125

    Question

    What is induced fit?

    Answer

    Substrate binding shifts the enzyme's shape into a form that better supports catalysis.

  126. Card 126

    Question

    Where does the Calvin cycle occur?

    Answer

    In the chloroplast stroma.

  127. Card 127

    Question

    What does glycolysis produce per glucose?

    Answer

    Two pyruvate, a net two ATP, and two NADH.

  128. Card 128

    Question

    How can cells drive an endergonic reaction?

    Answer

    They couple it to a sufficiently exergonic reaction so the combined free-energy change is negative.

  129. Card 129

    Question

    Why isn't an enzyme consumed by the reaction it catalyzes?

    Answer

    It returns to a reusable form after products leave the active site.

  130. Card 130

    Question

    What do photosynthetic pigments do?

    Answer

    They absorb particular wavelengths and transfer excitation energy into the light reactions.

  131. Card 131

    Question

    Does glycolysis require oxygen directly?

    Answer

    No. It can run without oxygen if NAD⁺ is regenerated.

  132. Card 132

    Question

    What does ATP hydrolysis commonly provide?

    Answer

    Usable free energy and a phosphate group that can change a molecule's reactivity or protein shape.

  133. Card 133

    Question

    How does substrate concentration affect rate at low concentrations?

    Answer

    Rate usually rises because more substrate molecules collide with available active sites.

  134. Card 134

    Question

    Why do chlorophyll-containing leaves reflect green light?

    Answer

    Chlorophyll absorbs green wavelengths less strongly than red and blue wavelengths.

  135. Card 135

    Question

    Where does pyruvate oxidation occur in a eukaryotic cell?

    Answer

    In the mitochondrial matrix.

  136. Card 136

    Question

    Why is ATP called an energy-coupling molecule?

    Answer

    Its hydrolysis links energy-releasing processes to cellular work.

  137. Card 137

    Question

    Why does enzyme rate plateau at high substrate concentration?

    Answer

    Most active sites are occupied, so enzyme amount becomes limiting.

  138. Card 138

    Question

    What is photolysis of water?

    Answer

    Light-driven splitting of water that supplies electrons and protons and releases oxygen.

  139. Card 139

    Question

    What happens during pyruvate oxidation?

    Answer

    Each pyruvate becomes acetyl-CoA, releasing carbon dioxide and reducing NAD⁺ to NADH.

  140. Card 140

    Question

    Why measure an initial enzyme rate?

    Answer

    Substrate depletion and product buildup have had less time to distort the rate.

  141. Card 141

    Question

    How can high temperature reduce enzyme activity?

    Answer

    Heat can disrupt interactions that maintain the enzyme's functional shape.

  142. Card 142

    Question

    What is photosystem II's key contribution?

    Answer

    It excites electrons and replaces them by oxidizing water.

  143. Card 143

    Question

    Where does the citric acid cycle occur in eukaryotes?

    Answer

    In the mitochondrial matrix.

  144. Card 144

    Question

    What is oxidation?

    Answer

    Loss of electrons, often accompanied by loss of hydrogen or gain of oxygen.

  145. Card 145

    Question

    Why does each enzyme have an optimal pH range?

    Answer

    pH changes charges on amino-acid side chains and can alter binding or folding.

  146. Card 146

    Question

    What does the photosynthetic electron transport chain build?

    Answer

    A proton gradient across the thylakoid membrane.

  147. Card 147

    Question

    What is the citric acid cycle's main energy role?

    Answer

    It oxidizes acetyl groups and transfers electrons to NADH and FADH₂, making a small amount of ATP.

  148. Card 148

    Question

    In a photosynthesis experiment, why keep leaf area constant?

    Answer

    Leaf area affects light capture and gas exchange, so changing it could confound the tested factor.

  149. Card 149

    Question

    How does a competitive inhibitor reduce enzyme activity?

    Answer

    It competes with substrate for the active site.

  150. Card 150

    Question

    How does chloroplast ATP synthase make ATP?

    Answer

    Protons flow from the thylakoid space to the stroma through ATP synthase, driving phosphorylation of ADP.

  151. Card 151

    Question

    Where is the respiratory electron transport chain located in eukaryotes?

    Answer

    In the inner mitochondrial membrane.

  152. Card 152

    Question

    What is reduction?

    Answer

    Gain of electrons, often accompanied by gain of hydrogen or loss of oxygen.

  153. Card 153

    Question

    How can extra substrate weaken competitive inhibition?

    Answer

    More substrate increases the chance that substrate, rather than inhibitor, occupies the active site.

  154. Card 154

    Question

    What is photosystem I's key contribution?

    Answer

    It re-energizes electrons used to reduce NADP⁺ to NADPH.

  155. Card 155

    Question

    What is oxygen's role in aerobic respiration?

    Answer

    It is the final electron acceptor and combines with electrons and protons to form water.

  156. Card 156

    Question

    A respiration graph gets steeper after temperature rises. What does the slope show?

    Answer

    A higher rate of the measured respiratory change, such as oxygen consumption per unit time.

  157. Card 157

    Question

    How does a noncompetitive inhibitor act?

    Answer

    It binds away from the active site and changes enzyme activity, often by altering shape.

  158. Card 158

    Question

    What products of the light reactions feed the Calvin cycle?

    Answer

    ATP and NADPH.

  159. Card 159

    Question

    How does electron transport create a proton gradient?

    Answer

    Released electron energy pumps protons from the matrix to the intermembrane space.

  160. Card 160

    Question

    What do NADH and FADH₂ carry?

    Answer

    High-energy electrons and associated hydrogen used in energy-transfer pathways.

  161. Card 161

    Question

    What is allosteric regulation?

    Answer

    A regulator binds at one site and changes activity at another site on the protein.

  162. Card 162

    Question

    What does carbon fixation accomplish?

    Answer

    It incorporates inorganic carbon dioxide into an organic molecule.

  163. Card 163

    Question

    What is oxidative phosphorylation?

    Answer

    ATP production powered by electron transport and chemiosmosis.

  164. Card 164

    Question

    Why use multiple biological replicates in a rate experiment?

    Answer

    They reveal natural variation and make the estimated treatment effect more reliable.

  165. Card 165

    Question

    What is fermentation's central purpose?

    Answer

    It regenerates NAD⁺ so glycolysis can continue without an active electron transport chain.

  166. Card 166

    Question

    How does feedback inhibition control a pathway?

    Answer

    A pathway's end product inhibits an earlier enzyme, reducing unnecessary production.

  167. Card 167

    Question

    What enzyme fixes carbon in the Calvin cycle?

    Answer

    Rubisco.

  168. Card 168

    Question

    How does mitochondrial ATP synthase make ATP?

    Answer

    Protons flow into the matrix through ATP synthase, driving ADP phosphorylation.

  169. Card 169

    Question

    Why do cells use stepwise electron transfers?

    Answer

    They release energy in manageable increments that can be captured instead of lost mostly as heat.

  170. Card 170

    Question

    What is a cofactor?

    Answer

    A nonprotein helper, often a metal ion or small organic coenzyme, required for some enzymes to function.

  171. Card 171

    Question

    What are the three broad phases of the Calvin cycle?

    Answer

    Carbon fixation, reduction, and regeneration of the carbon-dioxide acceptor RuBP.

  172. Card 172

    Question

    How does lactic-acid fermentation regenerate NAD⁺?

    Answer

    NADH reduces pyruvate to lactate, returning electrons to form NAD⁺.

  173. Card 173

    Question

    What is substrate-level phosphorylation?

    Answer

    An enzyme transfers a phosphate directly from an intermediate to ADP.

  174. Card 174

    Question

    Error bars overlap broadly between two treatments. What is a careful conclusion?

    Answer

    The graph alone does not show a clear difference; a suitable statistical analysis and design context are still needed.

  175. Card 175

    Question

    Why run an enzyme assay without enzyme?

    Answer

    It measures the uncatalyzed background change and tests whether enzyme is required.

  176. Card 176

    Question

    How does alcoholic fermentation regenerate NAD⁺?

    Answer

    Pyruvate loses carbon dioxide, and the remaining compound is reduced to ethanol as NADH becomes NAD⁺.

  177. Card 177

    Question

    What is G3P's role in photosynthesis?

    Answer

    It is a three-carbon product that can leave the Calvin cycle and help build carbohydrates.

  178. Card 178

    Question

    Why are mitochondrial cristae useful?

    Answer

    They increase inner-membrane area for electron transport chains and ATP synthase.

  179. Card 179

    Question

    What does phosphorylation often do to a molecule?

    Answer

    It adds a phosphate group that can increase reactivity or alter a protein's shape and activity.

  180. Card 180

    Question

    A mutation lowers an enzyme's maximum rate but not substrate binding. What is a plausible effect?

    Answer

    It may impair a catalytic step or reduce the number of functional enzyme molecules.

  181. Card 181

    Question

    Why must the Calvin cycle regenerate RuBP?

    Answer

    RuBP is the carbon-dioxide acceptor needed for another turn of fixation.

  182. Card 182

    Question

    A chemical lowers oxygen use but not glycolysis. Which stage is most directly implicated?

    Answer

    Aerobic electron transport or a process supplying it, because glycolysis itself does not consume oxygen.

  183. Card 183

    Question

    How would closed stomata affect photosynthesis?

    Answer

    Carbon dioxide entry falls, which can limit carbon fixation even when light is available.

  184. Card 184

    Question

    A plant receives green light only. Predict its photosynthetic rate.

    Answer

    It will usually be lower than under equally intense red or blue light because common chlorophylls absorb green poorly.

  185. Card 185

    Question

    Why does fermentation yield less ATP per glucose than aerobic respiration?

    Answer

    It relies on glycolysis alone and leaves much of glucose's chemical energy in reduced end products.

  186. Card 186

    Question

    How does low ATP affect respiration pathway activity?

    Answer

    It usually relieves inhibition of key enzymes, increasing fuel oxidation and ATP production.

  187. Card 187

    Question

    How can oxygen production estimate photosynthetic rate?

    Answer

    Oxygen is a light-reaction product, so its production per unit time can serve as a rate proxy under controlled conditions.

  188. Card 188

    Question

    What happens to electron transport if oxygen is removed?

    Answer

    The chain backs up because electrons lack a final acceptor; NADH accumulates and oxidative phosphorylation stops.

  189. Card 189

    Question

    Why does a light-response curve eventually level off?

    Answer

    Another factor, such as carbon dioxide supply, temperature, or enzyme capacity, becomes limiting.

  190. Card 190

    Question

    An uncoupler lets protons cross the inner mitochondrial membrane. What happens?

    Answer

    The gradient weakens, ATP production falls, and more energy is released as heat even if electron transport continues.

  191. Card 191

    Question

    What is direct-contact signaling?

    Answer

    A membrane-bound molecule or cell junction communicates with an adjacent cell.

  192. Card 192

    Question

    What are the three broad stages of cell signaling?

    Answer

    Reception, transduction, and response.

  193. Card 193

    Question

    How can a receptor mutation block a response even when ligand is present?

    Answer

    The receptor may fail to bind ligand, change shape, or activate the first relay protein.

  194. Card 194

    Question

    What is negative feedback?

    Answer

    A response reduces the original stimulus, helping stabilize a variable near a functional range.

  195. Card 195

    Question

    What happens during G1 phase?

    Answer

    The cell grows, performs normal functions, and prepares for DNA replication.

  196. Card 196

    Question

    Cells show response values of 2, 7, and 18 after rising ligand doses. Describe the trend.

    Answer

    The response increases with ligand dose across the tested range.

  197. Card 197

    Question

    What happens during reception?

    Answer

    A ligand binds its receptor and changes the receptor's activity or shape.

  198. Card 198

    Question

    What is paracrine signaling?

    Answer

    A cell releases a local regulator that acts on nearby target cells.

  199. Card 199

    Question

    What happens during S phase?

    Answer

    DNA is replicated, producing sister chromatids for each chromosome.

  200. Card 200

    Question

    A response occurs without ligand. What pathway defect is plausible?

    Answer

    A receptor or downstream relay protein may be constitutively active.

  201. Card 201

    Question

    What happens during signal transduction?

    Answer

    Intracellular steps relay and often amplify information from the activated receptor.

  202. Card 202

    Question

    What is synaptic signaling?

    Answer

    A neuron releases neurotransmitter across a short synaptic gap to a target cell.

  203. Card 203

    Question

    What happens during G2 phase?

    Answer

    The cell grows, checks replicated DNA, and prepares the machinery for division.

  204. Card 204

    Question

    Why compare receptor-positive and receptor-negative cells?

    Answer

    The comparison tests whether the receptor is necessary for the observed response.

  205. Card 205

    Question

    What counts as a cellular response?

    Answer

    A change in gene expression, enzyme activity, ion flow, secretion, movement, division, or another cell behavior.

  206. Card 206

    Question

    How does insulin participate in negative feedback?

    Answer

    High blood glucose promotes insulin release, which lowers blood glucose and reduces the original stimulus.

  207. Card 207

    Question

    What happens during mitosis?

    Answer

    A eukaryotic nucleus separates duplicated chromosomes into two nuclei.

  208. Card 208

    Question

    What is endocrine signaling?

    Answer

    Hormones travel through circulatory fluid to target cells that may be far away.

  209. Card 209

    Question

    What does a protein kinase do?

    Answer

    It transfers a phosphate from ATP to a target protein.

  210. Card 210

    Question

    A drug blocks a kinase, and the final response disappears. What is supported?

    Answer

    The kinase is required somewhere in that pathway under the tested conditions.

  211. Card 211

    Question

    What happens during cytokinesis?

    Answer

    The cytoplasm divides to form separate daughter cells.

  212. Card 212

    Question

    How does glucagon participate in glucose homeostasis?

    Answer

    Low blood glucose promotes glucagon release, which raises blood glucose toward the normal range.

  213. Card 213

    Question

    What does a protein phosphatase do?

    Answer

    It removes a phosphate group from a target protein.

  214. Card 214

    Question

    What is a ligand?

    Answer

    A signaling molecule that binds specifically to a receptor.

  215. Card 215

    Question

    What is the G1 checkpoint's broad role?

    Answer

    It checks size, nutrients, growth signals, and DNA condition before replication.

  216. Card 216

    Question

    Why can't one inhibitor experiment prove a protein's exact pathway position?

    Answer

    Off-target effects and indirect dependencies can produce the same outcome.

  217. Card 217

    Question

    Why are phosphorylation cascades reversible?

    Answer

    Kinases add phosphates, while phosphatases remove them and reset pathway components.

  218. Card 218

    Question

    What is positive feedback?

    Answer

    A response strengthens the initiating stimulus until a separate event stops the loop.

  219. Card 219

    Question

    What is the G2 checkpoint's broad role?

    Answer

    It checks whether DNA replication is complete and damage is repaired before mitosis.

  220. Card 220

    Question

    Why don't all cells respond to the same hormone?

    Answer

    Only cells with a compatible receptor and response machinery can respond.

  221. Card 221

    Question

    What is a second messenger?

    Answer

    A small intracellular molecule or ion that relays a signal after receptor activation.

  222. Card 222

    Question

    How can rescue with an active downstream protein map a pathway?

    Answer

    If the response returns despite an upstream block, the rescued protein likely acts downstream of that block.

  223. Card 223

    Question

    What does the spindle checkpoint verify?

    Answer

    Every chromosome is correctly attached to spindle microtubules before sister chromatids separate.

  224. Card 224

    Question

    Why is blood clotting a positive-feedback process?

    Answer

    Activated platelets recruit and activate more platelets until the break is sealed.

  225. Card 225

    Question

    Name two common second messengers.

    Answer

    Cyclic AMP and calcium ions.

  226. Card 226

    Question

    A mutant receptor binds ligand but never becomes phosphorylated. Predict downstream signaling.

    Answer

    It will likely fall or disappear if receptor phosphorylation is required to recruit relay proteins.

  227. Card 227

    Question

    How do cyclins regulate the cell cycle?

    Answer

    Their concentrations rise and fall, activating cyclin-dependent kinases at specific stages.

  228. Card 228

    Question

    Why must DNA replicate before mitosis?

    Answer

    Each daughter nucleus needs a complete copy of the genome.

  229. Card 229

    Question

    Where do receptors for many peptide hormones sit?

    Answer

    In the plasma membrane, because these polar ligands do not readily cross the lipid bilayer.

  230. Card 230

    Question

    How can a signaling pathway amplify a weak signal?

    Answer

    One activated component activates many downstream molecules at successive steps.

  231. Card 231

    Question

    What is the dependent variable in a ligand-dose experiment?

    Answer

    The measured response, such as reporter activity, enzyme phosphorylation, or ion concentration.

  232. Card 232

    Question

    What do cyclin-dependent kinases do?

    Answer

    When paired with cyclins, they phosphorylate targets that drive cell-cycle transitions.

  233. Card 233

    Question

    Why doesn't positive feedback usually maintain homeostasis by itself?

    Answer

    It drives change away from the starting state and needs an external stop.

  234. Card 234

    Question

    What is a G protein's signaling role?

    Answer

    It switches activity when bound to GTP and relays information from certain membrane receptors to effectors.

  235. Card 235

    Question

    How would you test whether calcium is required for a response?

    Answer

    Block the calcium rise while keeping other conditions matched, then compare the response with a vehicle control.

  236. Card 236

    Question

    What is apoptosis?

    Answer

    Programmed cell death that dismantles a cell in a controlled way.

  237. Card 237

    Question

    Where are receptors for many steroid hormones?

    Answer

    Inside the cell, where lipid-soluble hormones can bind after crossing the membrane.

  238. Card 238

    Question

    How can an ion-channel receptor create a rapid response?

    Answer

    Ligand binding opens or closes a pore, quickly changing ion movement and membrane conditions.

  239. Card 239

    Question

    Why test several ligand concentrations?

    Answer

    A dose–response series can reveal sensitivity, saturation, and whether effects scale with ligand.

  240. Card 240

    Question

    Why is apoptosis useful in multicellular organisms?

    Answer

    It removes damaged, infected, or unneeded cells with limited harm to neighbors.

  241. Card 241

    Question

    A thermostat-like pathway overshoots repeatedly. What defect is plausible?

    Answer

    Delayed sensing or response can make negative feedback correct too late.

  242. Card 242

    Question

    How can an intracellular receptor affect gene expression?

    Answer

    The ligand–receptor complex can act directly or indirectly as a transcription regulator.

  243. Card 243

    Question

    Cells lacking protein X divide despite DNA damage. Justify a checkpoint claim.

    Answer

    Protein X likely supports a DNA-damage checkpoint because its absence links damage with continued division; rescue or pathway tests would strengthen the claim.

  244. Card 244

    Question

    What aligns at the metaphase plate?

    Answer

    Duplicated chromosomes attached to spindle microtubules from opposite poles.

  245. Card 245

    Question

    How can failed checkpoints contribute to cancer?

    Answer

    Cells with damage or abnormal signals can keep dividing instead of pausing or dying.

  246. Card 246

    Question

    How can gap junctions support communication?

    Answer

    They connect neighboring animal-cell cytoplasms so small molecules and ions can pass directly.

  247. Card 247

    Question

    Why can the same ligand trigger different responses in two cell types?

    Answer

    The cells can express different receptors, relay proteins, targets, or genes.

  248. Card 248

    Question

    Two pathways share one relay protein. What can happen if that protein is blocked?

    Answer

    Both responses may weaken, showing pathway crosstalk or a shared component.

  249. Card 249

    Question

    During which mitotic stage do sister chromatids separate?

    Answer

    Anaphase.

  250. Card 250

    Question

    What defines a malignant tumor?

    Answer

    Its cells invade surrounding tissue and may spread to distant sites.

  251. Card 251

    Question

    How would loss of a feedback inhibitor affect a biosynthetic pathway?

    Answer

    The pathway may stay active and overproduce its end product.

  252. Card 252

    Question

    What ends a signaling response?

    Answer

    Ligand removal, receptor inactivation, GTP hydrolysis, messenger breakdown, or dephosphorylation can shut it down.

  253. Card 253

    Question

    A pathway diagram shows A activates B, and B inhibits C. Predict C after A activation.

    Answer

    C activity should decrease, assuming the shown links are the relevant controlling interactions.

  254. Card 254

    Question

    A phosphatase that normally turns off an activated relay protein is inhibited. Predict the effect on that pathway.

    Answer

    Phosphorylated targets may stay active longer, extending or strengthening the response.

  255. Card 255

    Question

    A drug prevents spindle formation. Where should the cycle stop?

    Answer

    At the spindle checkpoint before anaphase, because chromosomes cannot attach correctly.

  256. Card 256

    Question

    What is the purpose of meiosis?

    Answer

    It produces haploid cells and reshuffles inherited alleles for sexual reproduction.

  257. Card 257

    Question

    What is crossing over?

    Answer

    Exchange of corresponding DNA segments between nonsister chromatids of homologous chromosomes.

  258. Card 258

    Question

    What does Mendel's law of segregation describe?

    Answer

    An individual's two alleles for a gene separate into different gametes.

  259. Card 259

    Question

    Why do X-linked recessive traits often appear more frequently in XY individuals?

    Answer

    They have only one X chromosome, so one recessive allele on it can determine the phenotype.

  260. Card 260

    Question

    What is incomplete dominance?

    Answer

    The heterozygote has a phenotype intermediate between the two homozygotes.

  261. Card 261

    Question

    What does a chi-square goodness-of-fit test compare?

    Answer

    Observed category counts with counts expected under a stated model.

  262. Card 262

    Question

    What is a homologous chromosome pair?

    Answer

    Two chromosomes carrying the same gene locations, one inherited from each parent, possibly with different alleles.

  263. Card 263

    Question

    What does Mendel's law of independent assortment describe?

    Answer

    Alleles of genes on different chromosomes, or far apart on one chromosome, assort independently during gamete formation.

  264. Card 264

    Question

    What is genetic linkage?

    Answer

    Genes close together on the same chromosome tend to be inherited together.

  265. Card 265

    Question

    When does crossing over occur?

    Answer

    During prophase I after homologs pair.

  266. Card 266

    Question

    How do sister chromatids differ from homologous chromosomes?

    Answer

    Sister chromatids are replicated copies of one chromosome; homologs are the maternal and paternal versions of the same chromosome type.

  267. Card 267

    Question

    For Aa × Aa, what is the expected genotype ratio?

    Answer

    1 AA : 2 Aa : 1 aa.

  268. Card 268

    Question

    How can linked genes produce recombinant offspring?

    Answer

    Crossing over can exchange DNA between the gene locations.

  269. Card 269

    Question

    What is the usual null hypothesis for a Mendelian chi-square test?

    Answer

    Any difference between observed and expected counts is due to chance sampling under the proposed inheritance model.

  270. Card 270

    Question

    What happens to homologous chromosomes in meiosis I?

    Answer

    They pair and then separate into different cells.

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  271. Card 271

    Question

    For Aa × Aa with complete dominance, what is the expected phenotype ratio?

    Answer

    3 dominant phenotype : 1 recessive phenotype.

  272. Card 272

    Question

    How does crossing over increase variation?

    Answer

    It creates chromosomes with new combinations of parental alleles.

  273. Card 273

    Question

    What does recombination frequency estimate?

    Answer

    Relative distance between linked genes; higher frequency generally means greater separation, up to the 50% limit.

  274. Card 274

    Question

    What happens to sister chromatids in meiosis II?

    Answer

    Their centromeres separate, and the chromatids move into different cells.

  275. Card 275

    Question

    What rule finds the probability of either of two mutually exclusive outcomes?

    Answer

    Add their individual probabilities.

  276. Card 276

    Question

    What is codominance?

    Answer

    Both alleles contribute distinct, detectable products or traits in the heterozygote.

  277. Card 277

    Question

    How is a chi-square contribution calculated for one category?

    Answer

    Subtract expected from observed, square the difference, and divide by expected.

  278. Card 278

    Question

    When do homologous chromosomes pair as tetrads?

    Answer

    During prophase I.

  279. Card 279

    Question

    What rule finds the probability that independent events both occur?

    Answer

    Multiply their individual probabilities.

  280. Card 280

    Question

    What is independent assortment?

    Answer

    Each homologous pair orients independently at metaphase I, producing many maternal–paternal chromosome combinations.

  281. Card 281

    Question

    Why can't recombination frequency exceed 50%?

    Answer

    At 50%, recombinant and parental combinations are equally common and the genes behave as if unlinked.

  282. Card 282

    Question

    What aligns at the metaphase I plate?

    Answer

    Homologous pairs, with each homolog attached toward an opposite pole.

  283. Card 283

    Question

    What is a test cross?

    Answer

    Crossing an individual with a dominant phenotype to a homozygous recessive individual to infer the unknown genotype.

  284. Card 284

    Question

    How can one gene have multiple alleles?

    Answer

    More than two allele forms can exist in the population, although one diploid individual carries at most two.

  285. Card 285

    Question

    How are total chi-square and category contributions related?

    Answer

    Total chi-square is the sum of all category contributions.

  286. Card 286

    Question

    What separates during anaphase I?

    Answer

    Homologous chromosomes; sister chromatids remain joined.

  287. Card 287

    Question

    How does random fertilization increase variation?

    Answer

    Any one genetically varied gamete from one parent can fuse with any compatible gamete from the other.

  288. Card 288

    Question

    A test cross yields about half recessive offspring. What genotype is supported for the unknown parent?

    Answer

    Heterozygous.

  289. Card 289

    Question

    What is nondisjunction?

    Answer

    Failure of homologous chromosomes or sister chromatids to separate normally.

  290. Card 290

    Question

    What aligns during metaphase II?

    Answer

    Individual duplicated chromosomes in each haploid cell.

  291. Card 291

    Question

    What is polygenic inheritance?

    Answer

    Multiple genes contribute to one trait, often producing continuous phenotypic variation.

  292. Card 292

    Question

    For a simple goodness-of-fit test, how are degrees of freedom found?

    Answer

    Number of categories minus one.

  293. Card 293

    Question

    Which meiotic events create variation before fertilization?

    Answer

    Crossing over and independent assortment.

  294. Card 294

    Question

    How does ploidy change during meiosis?

    Answer

    Homolog separation reduces diploid cells to haploid cells; meiosis II separates chromatids without another ploidy reduction.

  295. Card 295

    Question

    What pedigree pattern often suggests a recessive trait?

    Answer

    Unaffected parents can have an affected child, if both parents carry the allele.

  296. Card 296

    Question

    How can meiotic nondisjunction affect gametes?

    Answer

    It can produce gametes with an extra or missing chromosome.

  297. Card 297

    Question

    What is pleiotropy?

    Answer

    One gene influences multiple phenotypic traits.

  298. Card 298

    Question

    Why is there no second DNA replication before meiosis II?

    Answer

    The goal is to separate existing sister chromatids, not duplicate the genome again.

  299. Card 299

    Question

    What does a p-value below the chosen threshold support?

    Answer

    Rejecting the null model because the observed deviation would be unlikely if that model were correct.

  300. Card 300

    Question

    Why are siblings genetically different even with the same parents?

    Answer

    They inherit different allele combinations through crossing over, independent assortment, and random fertilization.

  301. Card 301

    Question

    Why do small families often deviate from expected Mendelian ratios?

    Answer

    Probability ratios describe long-run expectations; random sampling variation is large with few offspring.

  302. Card 302

    Question

    A diploid cell has six chromosomes. How many chromosomes should each normal meiotic product have?

    Answer

    Three.

  303. Card 303

    Question

    A trisomic zygote forms after fertilization. What meiotic error is a likely cause?

    Answer

    Nondisjunction produced a gamete carrying an extra copy of that chromosome.

  304. Card 304

    Question

    Why can identical genotypes show different phenotypes?

    Answer

    Environmental conditions and developmental variation can alter gene expression or trait development.

  305. Card 305

    Question

    What does failing to reject a genetic null hypothesis mean?

    Answer

    The data do not show a significant departure from the model; they do not prove the model true.

  306. Card 306

    Question

    How do DNA and RNA sugars differ?

    Answer

    DNA contains deoxyribose; RNA contains ribose.

  307. Card 307

    Question

    What does semiconservative DNA replication produce?

    Answer

    Each daughter DNA molecule contains one original strand and one newly synthesized strand.

  308. Card 308

    Question

    What is transcription?

    Answer

    Synthesis of RNA using DNA as a template.

  309. Card 309

    Question

    What is a point mutation?

    Answer

    A change affecting one nucleotide pair.

  310. Card 310

    Question

    What is an operon?

    Answer

    A group of prokaryotic genes controlled together and transcribed from one promoter.

  311. Card 311

    Question

    Why can muscle and nerve cells differ despite having the same genome?

    Answer

    They express different sets and amounts of genes.

  312. Card 312

    Question

    What must a virus use from its host?

    Answer

    Host resources and at least some host-cell machinery to copy or express its genome and produce new particles.

  313. Card 313

    Question

    What does PCR do?

    Answer

    It amplifies a chosen DNA region through repeated cycles of strand separation, primer binding, and extension.

  314. Card 314

    Question

    What enzyme performs transcription?

    Answer

    RNA polymerase.

  315. Card 315

    Question

    What does helicase do during replication?

    Answer

    It unwinds the double helix and separates the template strands.

  316. Card 316

    Question

    How does a repressor reduce transcription?

    Answer

    It binds regulatory DNA and blocks or hinders transcription machinery.

  317. Card 317

    Question

    What is a silent mutation?

    Answer

    A nucleotide change that does not change the encoded amino acid.

  318. Card 318

    Question

    What does a promoter do?

    Answer

    It marks where transcription machinery assembles and helps set the transcription start and direction.

  319. Card 319

    Question

    What does topoisomerase do ahead of a replication fork?

    Answer

    It relieves twisting strain caused by DNA unwinding.

  320. Card 320

    Question

    How does an inducer affect an inducible operon?

    Answer

    It disables the repressor or otherwise turns transcription on when the pathway's substrate is present.

  321. Card 321

    Question

    How do DNA and RNA bases differ?

    Answer

    DNA uses thymine, while RNA uses uracil; both also use adenine, cytosine, and guanine.

  322. Card 322

    Question

    Which DNA strand does RNA polymerase read?

    Answer

    The template strand, read 3′→5′ while RNA is built 5′→3′.

  323. Card 323

    Question

    Why is an RNA primer needed for DNA replication?

    Answer

    DNA polymerase can extend an existing 3′ end but cannot start a strand from nothing.

  324. Card 324

    Question

    How does a corepressor affect a repressible operon?

    Answer

    It activates a repressor, turning off genes when the pathway's end product is abundant.

  325. Card 325

    Question

    What is a missense mutation?

    Answer

    A nucleotide change that substitutes one amino acid for another.

  326. Card 326

    Question

    How does an mRNA sequence relate to the coding DNA strand?

    Answer

    It matches the coding strand except RNA has uracil in place of thymine.

  327. Card 327

    Question

    What does primase do?

    Answer

    It builds short RNA primers.

  328. Card 328

    Question

    Why is the lac operon strongly expressed when lactose is present and glucose is scarce?

    Answer

    Lactose relieves repression, while low glucose supports positive activation of transcription.

  329. Card 329

    Question

    Why are primers essential in PCR?

    Answer

    They define the target boundaries and provide 3′ ends for DNA polymerase.

  330. Card 330

    Question

    What is the primary RNA transcript in a eukaryote?

    Answer

    The initial RNA copy before processing.

  331. Card 331

    Question

    In which direction does DNA polymerase synthesize DNA?

    Answer

    5′→3′ by adding nucleotides to a 3′ end.

  332. Card 332

    Question

    Why is the trp operon usually off when tryptophan is abundant?

    Answer

    Tryptophan acts as a corepressor, enabling repression of biosynthetic genes.

  333. Card 333

    Question

    What holds complementary DNA bases together?

    Answer

    Hydrogen bonds: adenine pairs with thymine, and cytosine pairs with guanine.

  334. Card 334

    Question

    What happens during RNA splicing?

    Answer

    Introns are removed and exons are joined.

  335. Card 335

    Question

    Why is the leading strand synthesized continuously?

    Answer

    Its template orientation lets polymerase follow the replication fork while synthesizing 5′→3′.

  336. Card 336

    Question

    How can histone acetylation affect transcription?

    Answer

    It often loosens chromatin and makes DNA more accessible to transcription machinery.

  337. Card 337

    Question

    What is a nonsense mutation?

    Answer

    A nucleotide change that creates a premature stop codon.

  338. Card 338

    Question

    What do the 5′ cap and poly-A tail help do?

    Answer

    They protect eukaryotic mRNA and support export and translation.

  339. Card 339

    Question

    Why is the lagging strand synthesized in fragments?

    Answer

    Its template orientation forces repeated 5′→3′ synthesis away from the moving fork.

  340. Card 340

    Question

    How can DNA methylation near a promoter affect transcription?

    Answer

    It often reduces transcription by limiting access or recruiting repressive proteins.

  341. Card 341

    Question

    How does gel electrophoresis separate DNA fragments?

    Answer

    An electric field pulls negatively charged DNA through a matrix; smaller fragments usually travel farther.

  342. Card 342

    Question

    How can alternative splicing increase protein diversity?

    Answer

    Different exon combinations from one transcript can produce different mRNAs and polypeptides.

  343. Card 343

    Question

    What are Okazaki fragments?

    Answer

    Short DNA segments made on the lagging strand.

  344. Card 344

    Question

    What does a transcription factor do?

    Answer

    It binds regulatory DNA and helps increase or decrease transcription of specific genes.

  345. Card 345

    Question

    Why are DNA strands antiparallel?

    Answer

    Their sugar–phosphate backbones run in opposite 5′→3′ directions.

  346. Card 346

    Question

    What is translation?

    Answer

    Ribosomes use an mRNA codon sequence to build a polypeptide.

  347. Card 347

    Question

    What does DNA ligase do?

    Answer

    It seals breaks in the sugar–phosphate backbone, joining DNA fragments.

  348. Card 348

    Question

    What is a frameshift mutation?

    Answer

    An insertion or deletion not in multiples of three that shifts downstream codon grouping.

  349. Card 349

    Question

    How can an enhancer influence a distant promoter?

    Answer

    DNA looping brings enhancer-bound activators near the transcription machinery.

  350. Card 350

    Question

    What does a codon specify?

    Answer

    An amino acid or a translation stop signal.

  351. Card 351

    Question

    What do restriction enzymes do?

    Answer

    They cut DNA at particular recognition sequences.

  352. Card 352

    Question

    What gives a nucleic-acid strand its 5′ and 3′ ends?

    Answer

    The chemical groups on the sugar: a 5′ phosphate end and a 3′ hydroxyl end.

  353. Card 353

    Question

    How does proofreading improve replication accuracy?

    Answer

    DNA polymerases detect and replace many incorrectly paired nucleotides.

  354. Card 354

    Question

    What does a tRNA anticodon do?

    Answer

    It base-pairs with an mRNA codon so the attached amino acid is placed correctly.

  355. Card 355

    Question

    Why can a promoter mutation affect protein amount?

    Answer

    It can change transcription-factor or RNA-polymerase binding and alter transcription rate.

  356. Card 356

    Question

    How can microRNA reduce gene expression?

    Answer

    It base-pairs with target mRNA and promotes degradation or blocks translation.

  357. Card 357

    Question

    What maintains a differentiated cell's identity?

    Answer

    Stable regulatory networks and chromatin states keep characteristic genes active or silent.

  358. Card 358

    Question

    What are the ribosome's broad roles?

    Answer

    It positions mRNA and tRNAs and catalyzes peptide-bond formation.

  359. Card 359

    Question

    How can an RNA virus generate genetic variation quickly?

    Answer

    Many viral RNA polymerases lack strong proofreading, so replication introduces mutations frequently.

  360. Card 360

    Question

    What can bacterial transformation demonstrate?

    Answer

    Cells can take up external DNA and express a selectable or observable trait.

  361. Card 361

    Question

    Why is RNA usually more structurally varied than double-stranded DNA?

    Answer

    A single RNA strand can fold back on itself through internal base pairing.

  362. Card 362

    Question

    What usually marks translation initiation?

    Answer

    A start codon positioned with an initiator tRNA and ribosomal subunits.

  363. Card 363

    Question

    What problem do telomeres help solve?

    Answer

    They protect chromosome ends from losing essential genes during repeated linear-DNA replication.

  364. Card 364

    Question

    Why can an intron splice-site mutation affect protein sequence?

    Answer

    Incorrect splicing can remove exon sequence or retain intron sequence in the mature mRNA.

  365. Card 365

    Question

    How can protein degradation regulate a pathway quickly?

    Answer

    Destroying a key protein lowers its activity without waiting for transcription to change.

  366. Card 366

    Question

    What happens at a stop codon?

    Answer

    A release factor ends translation and frees the polypeptide.

  367. Card 367

    Question

    How can a signal change cell specialization?

    Answer

    It can activate transcription factors that launch a new gene-expression program.

  368. Card 368

    Question

    What is a retrovirus's information flow?

    Answer

    Viral RNA is reverse-transcribed into DNA, which can integrate into the host genome.

  369. Card 369

    Question

    What does DNA sequencing reveal directly?

    Answer

    The order of nucleotides in the analyzed DNA; biological effects require further interpretation.

  370. Card 370

    Question

    Why is the genetic code called redundant?

    Answer

    More than one codon can specify the same amino acid.

  371. Card 371

    Question

    Where does nucleotide sequence store information?

    Answer

    The order of bases encodes information that can be copied, transcribed, or translated.

  372. Card 372

    Question

    Why is replication called bidirectional?

    Answer

    Two forks usually move away from each origin in opposite directions.

  373. Card 373

    Question

    Why doesn't every DNA mutation change phenotype?

    Answer

    It may occur outside a functional sequence, be silent, have a mild effect, or be masked by another allele or environment.

  374. Card 374

    Question

    How does a free ribosome's product usually differ from a rough-ER ribosome's product?

    Answer

    Free ribosomes often make cytosolic proteins; ER-bound ribosomes make many secreted, membrane, and endomembrane proteins.

  375. Card 375

    Question

    Why can one signal coordinate many genes?

    Answer

    A shared transcription regulator or signaling pathway can control multiple target promoters.

  376. Card 376

    Question

    Why does cell specialization depend on selective gene expression rather than gene loss?

    Answer

    Most specialized cells retain the genome but use only the genes needed for their role.

  377. Card 377

    Question

    Why are viruses not described as independently living cells?

    Answer

    They lack cellular metabolism and cannot reproduce without a host cell.

  378. Card 378

    Question

    A coding DNA triplet is 5′-ATG-3′. What is the matching mRNA codon?

    Answer

    5′-AUG-3′.

  379. Card 379

    Question

    A PCR band is absent. Why isn't gene absence the only explanation?

    Answer

    Poor DNA quality, wrong primers, inhibitors, or failed reaction conditions can also prevent amplification.

  380. Card 380

    Question

    Why can protein function require steps after translation?

    Answer

    The polypeptide may need folding, cleavage, chemical modification, or assembly with other subunits.

  381. Card 381

    Question

    How do fossils support evolution?

    Answer

    They document organisms and transitions through time, including appearance, change, and extinction.

  382. Card 382

    Question

    What conditions are required for natural selection?

    Answer

    Individuals vary, some variation is heritable, and variants differ in survival or reproductive success in that environment.

  383. Card 383

    Question

    What is artificial selection?

    Answer

    Humans choose which organisms reproduce based on desired heritable traits.

  384. Card 384

    Question

    What does an allele frequency measure?

    Answer

    The fraction of all copies of a gene in a population represented by one allele.

  385. Card 385

    Question

    What does a node on a phylogenetic tree represent?

    Answer

    A common ancestor where descendant lineages diverge.

  386. Card 386

    Question

    What is biological speciation?

    Answer

    Evolution of reproductive isolation between populations, producing independently evolving lineages.

  387. Card 387

    Question

    What is extinction?

    Answer

    Permanent loss of a species when no living members remain.

  388. Card 388

    Question

    A pesticide-treated population becomes mostly resistant. What evidence distinguishes selection from acclimation?

    Answer

    Resistance should be heritable and increase across generations through differential reproduction, not just appear temporarily in exposed individuals.

  389. Card 389

    Question

    What changes during evolution by natural selection?

    Answer

    Allele frequencies in a population across generations.

  390. Card 390

    Question

    For two alleles under Hardy–Weinberg notation, what does p + q equal?

    Answer

    1.

  391. Card 391

    Question

    What is a clade?

    Answer

    An ancestor and all of its descendants.

  392. Card 392

    Question

    What does homologous anatomy suggest?

    Answer

    Similar underlying structures with different functions can indicate inheritance from a common ancestor.

  393. Card 393

    Question

    Do individual organisms evolve by natural selection?

    Answer

    No. Individuals are selected; populations evolve as inherited variants change in frequency.

  394. Card 394

    Question

    Under Hardy–Weinberg equilibrium, what does p² represent?

    Answer

    Expected frequency of one homozygous genotype.

  395. Card 395

    Question

    What is a shared derived character?

    Answer

    A trait that evolved in a common ancestor and helps identify one of its descendant clades.

  396. Card 396

    Question

    What is mutation's evolutionary role?

    Answer

    It creates new alleles, the ultimate source of new genetic variation.

  397. Card 397

    Question

    What is biological fitness?

    Answer

    Relative contribution of viable, reproducing offspring to the next generation in a particular environment.

  398. Card 398

    Question

    Under Hardy–Weinberg equilibrium, what does 2pq represent?

    Answer

    Expected frequency of heterozygotes.

  399. Card 399

    Question

    Which two tips on a tree are most closely related?

    Answer

    Those sharing the most recent common ancestor, regardless of how close their names appear on the page.

  400. Card 400

    Question

    What is a vestigial structure?

    Answer

    A reduced feature inherited from ancestors that has lost much or all of its earlier function.

  401. Card 401

    Question

    What is an adaptation?

    Answer

    A heritable trait that became common because it improved fitness in past environments.

  402. Card 402

    Question

    Under Hardy–Weinberg equilibrium, what does q² represent?

    Answer

    Expected frequency of the other homozygous genotype.

  403. Card 403

    Question

    How does recombination affect evolution?

    Answer

    It reshuffles existing alleles into new combinations but does not itself create new alleles.

  404. Card 404

    Question

    Does rotating branches around a node change relationships?

    Answer

    No. The branching pattern stays the same.

  405. Card 405

    Question

    Why isn't an adaptation always beneficial in every setting?

    Answer

    Fitness effects depend on the environment and can involve tradeoffs.

  406. Card 406

    Question

    What are the Hardy–Weinberg assumptions?

    Answer

    A very large population, random mating, no mutation, no migration, and no natural selection at the locus.

  407. Card 407

    Question

    How can embryological similarities support common ancestry?

    Answer

    Shared developmental patterns can reflect inherited developmental genes and pathways.

  408. Card 408

    Question

    What is gene flow?

    Answer

    Movement of alleles between populations through migration and reproduction.

  409. Card 409

    Question

    Does natural selection create needed mutations?

    Answer

    No. Mutations arise without regard to need; selection changes the frequencies of their inherited effects.

  410. Card 410

    Question

    Why is Hardy–Weinberg equilibrium useful?

    Answer

    It provides a null model for detecting or reasoning about evolutionary change.

  411. Card 411

    Question

    Does left-to-right tip order show evolutionary progress?

    Answer

    No. Tip order is a drawing choice, not a ranking from primitive to advanced.

  412. Card 412

    Question

    What is allopatric speciation?

    Answer

    Geographic separation reduces gene flow, allowing populations to diverge.

  413. Card 413

    Question

    What is directional selection?

    Answer

    Selection favors one end of a phenotypic range, shifting the population mean.

  414. Card 414

    Question

    If q² = 0.09, what is q?

    Answer

    0.30.

  415. Card 415

    Question

    Why is DNA sequence similarity evidence for relatedness?

    Answer

    Related lineages inherit sequences from common ancestors, with differences accumulating over time.

  416. Card 416

    Question

    How does gene flow often affect differences between populations?

    Answer

    It tends to make allele frequencies more similar.

  417. Card 417

    Question

    What is stabilizing selection?

    Answer

    Selection favors intermediate phenotypes and removes extremes.

  418. Card 418

    Question

    If q = 0.30, what is p?

    Answer

    0.70.

  419. Card 419

    Question

    What can branch length mean?

    Answer

    Only what the figure defines—sometimes time or amount of change, and sometimes nothing quantitative.

  420. Card 420

    Question

    What is sympatric speciation?

    Answer

    Reproductive isolation evolves without geographic separation, for example through polyploidy or strong niche and mating differences.

  421. Card 421

    Question

    What is disruptive selection?

    Answer

    Selection favors both extremes over intermediate phenotypes.

  422. Card 422

    Question

    If p = 0.70 and q = 0.30, what is 2pq?

    Answer

    0.42.

  423. Card 423

    Question

    Why include an untreated population in a selection experiment?

    Answer

    It shows how allele or trait frequencies change without the selective treatment.

  424. Card 424

    Question

    Why is the nearly universal genetic code evidence of common ancestry?

    Answer

    A deeply conserved information system is most simply explained by inheritance from early shared ancestors.

  425. Card 425

    Question

    What is balancing selection?

    Answer

    Natural selection that maintains two or more alleles in a population, such as through heterozygote advantage or selection that varies across environments.

  426. Card 426

    Question

    What is genetic drift?

    Answer

    Random change in allele frequencies caused by chance sampling across generations.

  427. Card 427

    Question

    If 16% of a Hardy–Weinberg population shows a recessive phenotype, what is q?

    Answer

    0.40, because q is the square root of 0.16.

  428. Card 428

    Question

    Why use an outgroup in tree analysis?

    Answer

    It helps infer which character states are ancestral versus derived in the focal group.

  429. Card 429

    Question

    What is a prezygotic barrier?

    Answer

    A barrier that prevents mating or fertilization.

  430. Card 430

    Question

    Allele A rises from 0.20 to 0.45. Describe the evolutionary result.

    Answer

    The population evolved at that locus because allele frequency changed.

  431. Card 431

    Question

    How does biogeography support evolution?

    Answer

    Species distributions often match isolation history, dispersal, and descent from nearby ancestors.

  432. Card 432

    Question

    What is sexual selection?

    Answer

    Differences in mating success drive changes in traits that affect mate attraction or competition.

  433. Card 433

    Question

    When is genetic drift strongest?

    Answer

    In small populations.

  434. Card 434

    Question

    Why can a rare recessive allele persist?

    Answer

    Selection cannot remove copies hidden in heterozygotes as efficiently as copies expressed in homozygotes.

  435. Card 435

    Question

    How can molecular data revise a phylogenetic tree?

    Answer

    Sequence comparisons can reveal relationships not obvious from morphology or distinguish convergence from homology.

  436. Card 436

    Question

    What is a postzygotic barrier?

    Answer

    A barrier that reduces hybrid survival, fertility, or later-generation success after fertilization.

  437. Card 437

    Question

    How can rapid environmental change increase extinction risk?

    Answer

    Populations may lack enough suitable variation or time to adapt or move.

  438. Card 438

    Question

    A small island population loses alleles after a storm. Which mechanism is most direct?

    Answer

    Genetic drift through a bottleneck.

  439. Card 439

    Question

    What is convergent evolution?

    Answer

    Unrelated lineages independently evolve similar traits under similar selective pressures.

  440. Card 440

    Question

    Why can antibiotic resistance spread rapidly?

    Answer

    Treatment strongly favors resistant variants already present or newly introduced, which leave more descendants.

  441. Card 441

    Question

    What is a bottleneck effect?

    Answer

    A sharp population reduction leaves a random, often less diverse sample of the original gene pool.

  442. Card 442

    Question

    How do genotype counts yield allele frequency?

    Answer

    Count two copies from each homozygote and one from each heterozygote, then divide by twice the number of diploid individuals.

  443. Card 443

    Question

    What is maximum parsimony in tree building?

    Answer

    Preferring the tree that requires the fewest evolutionary changes under the model.

  444. Card 444

    Question

    How can different breeding times isolate populations?

    Answer

    Temporal isolation prevents individuals from mating even when they share a location.

  445. Card 445

    Question

    Why can mass extinctions reshape evolution?

    Answer

    They remove many lineages and open ecological opportunities for survivors.

  446. Card 446

    Question

    Two similar traits evolved on distant tree branches. What explanation should be evaluated?

    Answer

    Convergent evolution under similar selection, alongside the possibility of an incorrect tree or unrecognized homology.

  447. Card 447

    Question

    Why are analogous structures weak evidence of close ancestry?

    Answer

    Their similar function may have evolved independently rather than from the same ancestral structure.

  448. Card 448

    Question

    Why doesn't natural selection produce perfection?

    Answer

    It works with existing variation under tradeoffs, historical constraints, chance, and changing environments.

  449. Card 449

    Question

    What is a founder effect?

    Answer

    A new population starts from a small, nonrepresentative sample of a source population.

  450. Card 450

    Question

    Observed genotypes differ from Hardy–Weinberg expectations. What is supported?

    Answer

    At least one model assumption may not hold, or sampling error may matter; the deviation alone does not identify the cause.

  451. Card 451

    Question

    Why is a phylogenetic tree a hypothesis?

    Answer

    It is an evidence-based reconstruction that can change when new data or methods appear.

  452. Card 452

    Question

    How can behavioral differences cause isolation?

    Answer

    Different courtship signals reduce mating between populations.

  453. Card 453

    Question

    What evidence can test origin-of-life hypotheses?

    Answer

    Chemistry experiments, geological records, molecular comparisons, and plausible self-replicating or membrane-forming systems.

  454. Card 454

    Question

    How should fitness be compared in an experiment?

    Answer

    Measure relative reproductive contribution, such as viable offspring, under the same environmental conditions.

  455. Card 455

    Question

    What does the fossil record not provide?

    Answer

    A complete sample of every organism or every transitional population.

  456. Card 456

    Question

    How can a neutral trait change in frequency?

    Answer

    Genetic drift can shift it by chance, especially in small populations.

  457. Card 457

    Question

    How can drift reduce adaptive potential?

    Answer

    It can remove alleles and lower genetic diversity needed under future environmental change.

  458. Card 458

    Question

    Why does a large population support Hardy–Weinberg stability?

    Answer

    Chance sampling has less effect on allele frequencies, reducing drift.

  459. Card 459

    Question

    If A and B share a more recent node with each other than either shares with C, what does that mean?

    Answer

    A and B are sister taxa and share a more recent common ancestor with each other than with C.

  460. Card 460

    Question

    What is adaptive radiation?

    Answer

    Rapid diversification of one ancestral lineage into species using different ecological roles.

  461. Card 461

    Question

    What can experiments producing organic molecules from simple chemicals show?

    Answer

    That some building blocks can form under modeled conditions; they do not recreate or prove the exact origin of life.

  462. Card 462

    Question

    A correlation links beak size with survival. Why isn't causation settled?

    Answer

    Other traits or habitats may covary with beak size; controlled or multivariable evidence is needed.

  463. Card 463

    Question

    Why does agreement among fossils, anatomy, and molecules strengthen an evolutionary claim?

    Answer

    Independent evidence types pointing to the same history make alternative explanations less plausible.

  464. Card 464

    Question

    A drought favors deeper beaks. What must be measured to show selection?

    Answer

    Heritable beak variation and differences in survival or reproduction linked to beak depth.

  465. Card 465

    Question

    Why can artificial selection produce unintended traits?

    Answer

    Selected genes may be linked to other alleles, and inbreeding can expose harmful recessive alleles.

  466. Card 466

    Question

    What data are needed to test Hardy–Weinberg genotype expectations?

    Answer

    Population genotype counts or reliable genotype frequencies for the locus.

  467. Card 467

    Question

    Why doesn't one living species count as the ancestor of another on a typical tree?

    Answer

    Living tips represent lineages that have both evolved since their shared ancestral lineage.

  468. Card 468

    Question

    Why can reduced gene flow accelerate divergence?

    Answer

    Populations retain separate mutations, drift independently, and respond to different selective pressures.

  469. Card 469

    Question

    Why are ribozymes relevant to early-life hypotheses?

    Answer

    RNA can both store information and catalyze reactions, offering a possible bridge before modern DNA–protein systems.

  470. Card 470

    Question

    What makes an evolutionary argument strong?

    Answer

    A clear claim, relevant population-level evidence, and reasoning that connects inheritance and differential reproduction to the observed change.

  471. Card 471

    Question

    How can a directional response help an organism?

    Answer

    Moving toward resources or away from hazards can improve survival and reproduction.

  472. Card 472

    Question

    What is a trophic level?

    Answer

    A feeding position in the flow of energy through an ecosystem.

  473. Card 473

    Question

    What processes move carbon into and out of biological molecules?

    Answer

    Photosynthesis fixes carbon; respiration, decomposition, and combustion release carbon dioxide.

  474. Card 474

    Question

    What does exponential population growth assume?

    Answer

    Resources are effectively unlimited and the per-capita growth rate stays constant.

  475. Card 475

    Question

    What is a density-dependent limiting factor?

    Answer

    Its effect strengthens as population density rises, such as competition, disease, or predation.

  476. Card 476

    Question

    What is a keystone species?

    Answer

    A species whose ecological effect is disproportionately large relative to its abundance.

  477. Card 477

    Question

    What are three levels of biodiversity?

    Answer

    Genetic diversity, species diversity, and ecosystem diversity.

  478. Card 478

    Question

    What is the independent variable in a fertilizer–algae experiment?

    Answer

    The fertilizer amount or nutrient concentration deliberately changed.

  479. Card 479

    Question

    What shape represents exponential growth over time?

    Answer

    A J-shaped curve.

  480. Card 480

    Question

    What do primary producers do?

    Answer

    They capture external energy and build organic molecules from inorganic carbon.

  481. Card 481

    Question

    What is a density-independent limiting factor?

    Answer

    Its effect is not primarily set by population density, such as a severe freeze or wildfire.

  482. Card 482

    Question

    Why is nitrogen fixation necessary?

    Answer

    Most organisms cannot use atmospheric nitrogen gas directly, so it must be converted to biologically available compounds.

  483. Card 483

    Question

    What does logistic growth add to the exponential model?

    Answer

    Growth slows as population size approaches carrying capacity.

  484. Card 484

    Question

    What is gross primary productivity?

    Answer

    The total rate at which producers capture energy in organic matter.

  485. Card 485

    Question

    What is competition?

    Answer

    An interaction in which organisms using the same limited resource reduce one another's access or fitness.

  486. Card 486

    Question

    What is ecological succession?

    Answer

    Change in community composition after new habitat forms or a disturbance alters an existing community.

  487. Card 487

    Question

    What shape represents ideal logistic growth?

    Answer

    An S-shaped curve.

  488. Card 488

    Question

    What is net primary productivity?

    Answer

    Gross primary productivity minus producers' respiratory energy use.

  489. Card 489

    Question

    Why does genetic diversity matter for conservation?

    Answer

    It increases the range of inherited responses available under disease or environmental change.

  490. Card 490

    Question

    What organisms perform much biological nitrogen fixation?

    Answer

    Certain prokaryotes, including free-living and symbiotic bacteria.

  491. Card 491

    Question

    What is carrying capacity?

    Answer

    The population size an environment can sustain over time under current conditions.

  492. Card 492

    Question

    Why is net primary productivity important to consumers?

    Answer

    It is the producer biomass and energy available for growth and the next trophic levels.

  493. Card 493

    Question

    What is competitive exclusion?

    Answer

    Species with identical limiting-resource niches cannot coexist indefinitely under stable conditions.

  494. Card 494

    Question

    How do primary and secondary succession differ?

    Answer

    Primary succession begins without developed soil; secondary succession begins where soil remains.

  495. Card 495

    Question

    Why can carrying capacity change?

    Answer

    Resources, habitat, climate, competitors, disease, and disturbance can change.

  496. Card 496

    Question

    Why does available energy decline up a food chain?

    Answer

    Organisms use much energy for metabolism and lose it as heat and waste rather than storing it as biomass.

  497. Card 497

    Question

    What is an ecosystem service?

    Answer

    A benefit people receive from ecosystems, such as pollination, water purification, soil formation, or climate regulation.

  498. Card 498

    Question

    What does nitrification do?

    Answer

    Microbes oxidize ammonium to nitrite and then nitrate.

  499. Card 499

    Question

    What does per-capita growth rate measure?

    Answer

    Population change per individual per unit time.

  500. Card 500

    Question

    What is ecological efficiency?

    Answer

    The percentage of energy or production transferred from one trophic level to the next.

  501. Card 501

    Question

    What is resource partitioning?

    Answer

    Competing species use different resources, places, or times, reducing direct overlap.

  502. Card 502

    Question

    What is resilience in an ecosystem?

    Answer

    The ability to recover structure or function after disturbance.

  503. Card 503

    Question

    How is population growth estimated from births, deaths, immigration, and emigration?

    Answer

    Births + immigration − deaths − emigration.

  504. Card 504

    Question

    If producers store 10,000 kJ and primary consumers receive 10%, how much do they receive?

    Answer

    1,000 kJ.

  505. Card 505

    Question

    How does habitat fragmentation affect populations?

    Answer

    It shrinks and isolates habitat, reducing movement and gene flow while increasing edge effects.

  506. Card 506

    Question

    Why sample several sites within each habitat?

    Answer

    Replication captures spatial variation and reduces the chance that one unusual site drives the result.

  507. Card 507

    Question

    A population grows from 200 to 230 in one year. What is its percent growth?

    Answer

    15%, because the increase of 30 divided by 200 is 0.15.

  508. Card 508

    Question

    What is a circadian rhythm?

    Answer

    An internal roughly 24-hour cycle that environmental cues can reset.

  509. Card 509

    Question

    Why are food webs more realistic than simple food chains?

    Answer

    Most species eat or are eaten by multiple species, creating connected pathways.

  510. Card 510

    Question

    What does denitrification do?

    Answer

    Microbes convert nitrate to nitrogen gases, returning nitrogen to the atmosphere.

  511. Card 511

    Question

    What characterizes an r-selected life-history strategy?

    Answer

    Many offspring, early reproduction, and relatively low investment per offspring in variable environments.

  512. Card 512

    Question

    What is mutualism?

    Answer

    An interaction that benefits both species.

  513. Card 513

    Question

    What is resistance in an ecosystem?

    Answer

    The ability to remain relatively unchanged during disturbance.

  514. Card 514

    Question

    How can climate change shift species ranges?

    Answer

    Organisms track suitable temperature, moisture, seasons, or interacting species when movement is possible.

  515. Card 515

    Question

    What characterizes a K-selected life-history strategy?

    Answer

    Fewer offspring, later reproduction, and higher investment per offspring near carrying capacity.

  516. Card 516

    Question

    A population curve levels near 800. What does the model suggest?

    Answer

    About 800 is the carrying capacity under those measured conditions, not a permanent universal value.

  517. Card 517

    Question

    How can seasonal cues affect reproduction?

    Answer

    Changes such as day length can trigger hormonal and behavioral shifts timed to favorable conditions.

  518. Card 518

    Question

    What role do decomposers play?

    Answer

    They break down dead material and waste, returning nutrients to forms other organisms can use.

  519. Card 519

    Question

    Why can phosphorus limit ecosystems?

    Answer

    It is essential but often released slowly from rocks and lacks a large atmospheric gas phase.

  520. Card 520

    Question

    What does a Type I survivorship curve show?

    Answer

    High survival through early and middle life, followed by a steep decline at older ages.

  521. Card 521

    Question

    What is commensalism?

    Answer

    One species benefits while the other has no clear benefit or harm.

  522. Card 522

    Question

    Why can diversity improve ecosystem stability?

    Answer

    Multiple species or response types can keep functions going when one component declines.

  523. Card 523

    Question

    Why can overharvesting destabilize a population?

    Answer

    Removal faster than replacement lowers abundance and can alter age structure or genetic diversity.

  524. Card 524

    Question

    Predator and prey peaks alternate over time. What can the graph establish?

    Answer

    Their abundances covary with a lag; the graph alone cannot prove the predator caused every prey change.

  525. Card 525

    Question

    What is acclimation?

    Answer

    A reversible phenotypic adjustment by an individual to an environmental change.

  526. Card 526

    Question

    Does energy cycle through an ecosystem?

    Answer

    No. Energy flows through and is ultimately dissipated as heat; matter cycles.

  527. Card 527

    Question

    How does the water cycle connect ecosystems?

    Answer

    Evaporation, transpiration, condensation, precipitation, runoff, and infiltration move water and dissolved materials.

  528. Card 528

    Question

    What does a Type II survivorship curve show?

    Answer

    A roughly constant mortality risk across ages.

  529. Card 529

    Question

    What is parasitism?

    Answer

    A parasite benefits while reducing its host's fitness.

  530. Card 530

    Question

    What is an invasive species?

    Answer

    A nonnative species that spreads and causes ecological, economic, or human-health harm.

  531. Card 531

    Question

    How can a wildlife corridor help fragmented populations?

    Answer

    It supports movement, recolonization, and gene flow between habitat patches.

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    Question

    How should biodiversity be compared when sample effort differs?

    Answer

    Standardize sampling effort or use a method that accounts for unequal effort before comparing.

  533. Card 533

    Question

    How does acclimation differ from adaptation?

    Answer

    Acclimation occurs within an individual; adaptation is an inherited population change across generations.

  534. Card 534

    Question

    How can removal of a top predator affect lower trophic levels?

    Answer

    It can trigger a trophic cascade by changing prey abundance and the organisms prey consume.

  535. Card 535

    Question

    Why can extra fertilizer cause low oxygen in water?

    Answer

    Nutrient enrichment drives algal growth; decomposition then consumes dissolved oxygen.

  536. Card 536

    Question

    What does a Type III survivorship curve show?

    Answer

    High early mortality with much better survival among those reaching later stages.

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    Question

    How can predation maintain diversity?

    Answer

    A predator can prevent one strong competitor from dominating the community.

  538. Card 538

    Question

    How can disturbance increase or decrease diversity?

    Answer

    Its effect depends on frequency and intensity; it may create habitat variety or eliminate sensitive species.

  539. Card 539

    Question

    Why protect multiple habitats rather than one small reserve?

    Answer

    Different habitats, disturbances, and climate trajectories preserve more species and ecological options.

  540. Card 540

    Question

    A restoration site gains species but not nutrient cycling. How should success be evaluated?

    Answer

    Use both composition and ecosystem-function measures; one metric alone gives an incomplete result.

A colorful biology collage links a cell, DNA helix, energy pathways, inherited variation, and an ecosystem.

540 cards

AP Biology Flashcards: Complete 8-Unit Course Review

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